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jimrandomh comments on If reductionism is the hammer, what nails are out there? - Less Wrong
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Hunger. People go on diets, notice that the diets leave them hungry, and fail to take the next step and determine which of the body's half-dozen hunger mechanisms is being triggered first.
Karl Smith of the blog Modeled Behavior frequently talks about body weight in a reductionist way (examples 1, 2, 3), without claiming to know how to fix obesity problems.