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Strange7 comments on Confidence levels inside and outside an argument - Less Wrong
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You shouldn't use Planck times unless the protean can rearrange themselves that quickly.
If the temperature is high enough that there's molecular movement at all, you could observe a collection of proteins every Planck-instant and see a (slightly) different arrangement each time. You might be stuck with similar ones, especially stable configurations, for a long time... but that's exactly the sort of bias that makes life possible.