Placebo Effect Benefits Patients Even When They Knowingly Take a Fake Pill
This is a little bit disturbing. (A kind of belief in belief, perhaps? Like, "I know a placebo is where you take a fake pill but it makes you feel better anyway if you believe it's real medicine, so I'd better believe this is real medicine!")
Though it's too bad they (apparently) didn't have a third group who received a placebo that they didn't know was a placebo, to compare the effect size.
Edit: Here's the actual study. RolfAndreassen points out that its results may not actually be strong evidence for what is being claimed.
I hope you mean disturbing in a good way, as in "I am committed to understanding the world, not finding evidence to support my view of how I want the world to look." I knowingly use the placebo effect on myself, relieving all sorts of things with ibuprofen. I figure the little bit of real pain relief the ibuprofen provides probably helps me to imagine myself better in other ways after I take it.
Perhaps the placebo effect works even when you know it is a sugar pill in the same way that essentially all optical illusions work even though we know they are illusions. Placebo effect probably reflects some deep wiring in us, which would hardly be expected to go away just because we know about it.
A possible defect in the study: it was based on people reporting improvement. That my knowing I took a fake pill might get me to report a fake improvement I don't think should be ruled out. I think I would like to see if Placebos can lower temperature in a fever, and compare the effectiveness of placebos when we tell you its a placebo and placebos given in all seriousness as an implied effective drug.
Ibuprofen isn't exactly a trivial pain reliever; it's decidedly more effective than tylenol and about the same effectiveness as codeine.