Alicorn comments on Luminosity (Twilight Fanfic) Discussion Thread 3 - Less Wrong
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"The Short Second Life of Bree Tanner" says it tastes funny relative to un-substance-laced human blood (but even "tainted" blood retains its delicious, nutritious, mind-bending, etc. nature.)
I rule that a half-vampire would be less sensitive to these flavor differences (but better able to actually discriminate between prey on this basis, due to not going sharkily insane around blood).
I think what tenshiko was asking (and what I'd anyway like to know ;) is if the drugs in the blood would affect (half-)vamps any. My guess would be that half-vamps yes, though probably milder and burned away more quickly?
I'm going to rule that the answer is usually no at normal doses, and, yeah, milder and briefer if the prey was really hopped up on the stuff.