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Molybdenumblue comments on Rationality Quotes: January 2011 - Less Wrong
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Agreed; I probably wouldn't have said "overwhelming evidence". But I do think there are still large gains to be made by vaccinating against more diseases, like, say, strep.
Revelation: The point of diminishing returns we would (in an ideal reach) is where health benefits are proportional to research dollars. Once a vaccine is researched, health benefits should be positive. However, variation, like the variation between regions, means that there are cases where an established vaccine has no benefits.