Whether or not the first cause argument should be a concern in science, i think Bertrand Russell summarizes its problems quite well:
"Perhaps the simplest and easiest to understand is the argument of the First Cause. It is maintained that everything we see in this world has a cause, and as you go back in the chain of causes further and further you must come to a First Cause, and to that First Cause you give the name of God. That argument, I suppose, does not carry very much weight nowadays, because, in the first place, cause is not quite what it used to be. The philosophers and the men of science have got going on cause, and it has not anything like the vitality that it used to have; but apart from that, you can see that the argument that there must be a First Cause is one that cannot have any validity. I may say that when I was a young man, and was debating these questions very seriously in my mind, I for a long time accepted the argument of the First Cause, until one day, at the age of eighteen, I read John Stuart Mill's Autobiography, and I there found this sentence: "My father taught me that the question, Who made me? cannot be answered, since it immediately suggests the further question, Who made God?" That very simple sentence showed me, as I still think, the fallacy in the argument of the First Cause. If everything must have a cause, then God must have a cause. If there can be anything without a cause, it may just as well be the world as God, so that there cannot be any validity in that argument. It is exactly of the same nature as the Hindu's view, that the world rested upon an elephant, and the elephant rested upon a tortoise; and when they said, "How about the tortoise?" the Indian said, "Suppose we change the subject." The argument is really no better than that. There is no reason why the world could not have come into being without a cause; nor, on the other hand, is there any reason why it should not have always existed. There is no reason to suppose that the world had a beginning at all. The idea that things must have a beginning is really due to the poverty of our imagination. Therefore, perhaps, I need not waste any more time upon the argument about the First Cause." http://www.positiveatheism.org/hist/russell0.htm
Eliezer Yudkowsky identifies scholarship as one of the Twelve Virtues of Rationality:
I think he's right, and I think scholarship doesn't get enough praise - even on Less Wrong, where it is regularly encouraged.
First, consider the evangelical atheist community to which I belong. There is a tendency for lay atheists to write "refutations" of theism without first doing a modicum of research on the current state of the arguments. This can get atheists into trouble when they go toe-to-toe with a theist who did do his homework. I'll share two examples:
The lesson I take from these and a hundred other examples is to employ the rationality virtue of scholarship. Stand on the shoulders of giants. We don't each need to cut our own path into a subject right from the point of near-total ignorance. That's silly. Just catch the bus on the road of knowledge paved by hundreds of diligent workers before you, and get off somewhere near where the road finally fades into fresh jungle. Study enough to have a view of the current state of the debate so you don't waste your time on paths that have already dead-ended, or on arguments that have already been refuted. Catch up before you speak up.
This is why, in more than 1000 posts on my own blog, I've said almost nothing that is original. Most of my posts instead summarize what other experts have said, in an effort to bring myself and my readers up to the level of the current debate on a subject before we try to make new contributions to it.
The Less Wrong community is a particularly smart and well-read bunch, but of course it doesn't always embrace the virtue of scholarship.
Consider the field of formal epistemology, an entire branch of philosophy devoted to (1) mathematically formalizing concepts related to induction, belief, choice, and action, and (2) arguing about the foundations of probability, statistics, game theory, decision theory, and algorithmic learning theory. These are central discussion topics at Less Wrong, and yet my own experience suggests that most Less Wrong readers have never heard of the entire field, let alone read any works by formal epistemologists, such as In Defense of Objective Bayesianism by Jon Williamson or Bayesian Epistemology by Luc Bovens and Stephan Hartmann.
Or, consider a recent post by Yudkowsky: Working hurts less than procrastinating, we fear the twinge of starting. The post attempts to make progress against procrastination by practicing single-subject phenomenology, rather than by first catching up with a quick summary of scientific research on procrastination. The post's approach to the problem looks inefficient to me. It's not standing on the shoulders of giants.
This post probably looks harsher than I mean it to be. After all, Less Wrong is pretty damn good at scholarship compared to most communities. But I think it could be better.
Here's my suggestion. Every time you're tempted to tackle a serious question in a subject on which you're not already an expert, ask yourself: "Whose giant shoulders can I stand on, here?"
Usually, you can answer the question by doing the following:
There are so many resources for learning available today, the virtue of scholarship has never in human history been so easy to practice.