There is a lot of PUA technique that amounts to an artificial means of improving unconscious or semi-conscious social signaling, and that strikes me as fairly inoffensive, but unless I'm one-minding badly here I don't think that part of the culture is a common target of criticism.

I think certain critics of the PUA culture don't even notice there are different parts to it, due to the outgroup homogeneity bias -- they just notice that certain PUAs say stuff they don't like, and generalize to PUAs in general. (The same thing happens to feminists.)