The obvious things to do with it (mass-immortality etc) are undermined the premise- from what I remember of the manga (good read when out of brainpower), Kami created the Dragon Balls so that mankind would have a hope even in the darkest of times- he failed to anticipate the Dragon Radar which made finding them trivial.
Upgraded Kami would probably realise that given the power of Shenron, he could create the Dragon Balls in such a way that, directly or indirectly if necessary, he could mold the world and prevent such dark times in the first place. It would then be down to whether he was smart enough to WANT everybody to be immortal.
Update: Discussion has moved on to a new thread.
The load more comments links are getting annoying (at least if you're not logged in), so it's time for a new Harry Potter and the Methods of Rationality discussion thread. We're also approaching the traditional 500-comment mark, but I think that hidden comments provide more appropriate joints to carve these threads at. So as of chapter 67, this is the place to share your thoughts about Eliezer Yudkowsky's Harry Potter fanfic.
The first 5 discussion threads are on the main page under the harry_potter tag. Threads 6 and on (including this one) are in the discussion section using its separate tag system. Also: one, two, three, four, five, six. The fanfiction.net author page is the central author-controlled HPMOR clearinghouse with links to the RSS feed, pdf version, TV Tropes pages, fan art, and more, and AdeleneDawner has kept an archive of Author's Notes.
As a reminder, it's often useful to start your comment by indicating which chapter you are commenting on.
Spoiler Warning: this thread is full of spoilers. With few exceptions, spoilers for MOR and canon are fair game to post, without warning or rot13. More specifically: