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Konkvistador comments on Steve Jobs' medical leave, riches and longevity - Less Wrong
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I don't know, what particularity impressed you about their foundation? Their effect on extreme poverty seems reasonable however looking at the results of their education initiatives I see few results that are too poor to not consider them a waste compared to other pursuits.
Bill Gates also hasn't had great success in the medical area: http://www.nytimes.com/2010/12/21/health/21gates.html
I used them as a contrast with leaving money to non-alleviating-suffering causes (Trump letting his children inherit it) or speculative-future-suffering causes (It's probably easier to convince someone to leave their money to a charity gets results today rather than one which tries to increase the chance of getting results tomorrow).
It's not really important to my point whether they are an effective charity or not, just that there aren't many single organizations with enough scale to handle Warren Buffet leaving all of several billion dollars to, and there aren't many examples of a Bill-Gates-rich person doing something quite like that.