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DSimon comments on Science: Do It Yourself - Less Wrong
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Poll: what studies would you do if ethics were not a constraint?
(Assuming that not only institutional ethics but my own sense of morality is not a constraint.)
A lot of the really interesting things we know about broad-scale human neurology, particularly some tricky stuff about the nature of consiousness, are due to the study of people who have suffered brain damage. If there were no ethical constraints, I would deliberately induce carefully controlled forms of brain damage on humans and observe the results.