What if we use 'human' as a rigid designator for unmodified-human. Then in case aliens convert people into paperclip-maximizers, they're no longer human, hence human_right no longer applies to them, but itself remains unchanged.
human_right still applies to them in the sense that they still should do what's human_right. That's the definition of should. (Remember, should refers to a specific set of terminal values, those that humans happen to have, called human_right) However, these modified humans, much like clippy, don't care about human_right and so won't be motivated to act based on human_right (except insofar as it helps make paperclips).
I'm not necessarily disagreeing with you because it's a little ambiguous how you used the word "applies." If you mean that the modified humans don't care about human_right anymore, I agree. If you mean that the modified humans shouldn't care about human_right, then I disagree.
In You Provably Can't Trust Yourself, Eliezer tried to figured out why his audience didn't understand his meta-ethics sequence even after they had followed him through philosophy of language and quantum physics. Meta-ethics is my specialty, and I can't figure out what Eliezer's meta-ethical position is. And at least at this point, professionals like Robin Hanson and Toby Ord couldn't figure it out, either.
Part of the problem is that because Eliezer has gotten little value from professional philosophy, he writes about morality in a highly idiosyncratic way, using terms that would require reading hundreds of posts to understand. I might understand Eliezer's meta-ethics better if he would just cough up his positions on standard meta-ethical debates like cognitivism, motivation, the sources of normativity, moral epistemology, and so on. Nick Beckstead recently told me he thinks Eliezer's meta-ethical views are similar to those of Michael Smith, but I'm not seeing it.
If you think you can help me (and others) understand Eliezer's meta-ethical theory, please leave a comment!
Update: This comment by Richard Chappell made sense of Eliezer's meta-ethics for me.