Depends on what organizational principles you are talking about. At the very generic level, the brain's extremely distributed architecture is already the direction computers are steadily moving towards out of necessity (with supercomputers farther ahead).

As for memristors, they will probably have many generic uses. They just also happen to be very powerful for cortex-like AGI applications.

The cortical model for an analog AGI circuit would be incredibly fast but it would be specific for AGI applications (which of course is still quite broad in scope). For regular computation you'd still use digital programmable chips.