Here's a personal anecdote: I recently asked a discussion group composed of non-rationalists if they would like to have the option of "living as long as you want in good health". I got a mixed response of "yes" and "maybe". On the other hand, even the "yes" people said that no way would they want cryonics, and they couldn't explain why. So not a complete success.
There's probably an absurdity bias going on in the rejection of cryonics (the dead just don't come back, and frozen people look dead). It also violates tradition (burying and incineration). And in our culture, the mere image of frozen bodies in a fridge has more disgusting connotations than happy ones.
So that's my speculation about why someone who never actually thought about cryonics might reject it. Maybe if we tell those people about these reasons, they could change their mind?
So, apparently appsumo is having a custom reddit bundle, a bundle meant to appeal to redditors, and 10% of the proceeds get donated. On the surface, doesn't sound _that_ interesting, except...
Take a closer look: http://appsumo.com/reddit-special-deal/ and find that the recipient of the donations will be... SENS!
I find this to be an interesting development. It wasn't the "custom transhumanist bundle" or "the custom sens bundle" but "the custom reddit bundle". Yes, "reddit" doesn't, in and of itself, count as extremely mainstream as such, but I'd say it's still an interesting development.