lukeprog comments on Heading Toward: No-Nonsense Metaethics - Less Wrong
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Just as a preview, I don't think the neuroscience of pleasure and desire are crucial for metaethics either, but they are useful for illustrative purposes of what possible moral reductions could mean. They can bring some clarity to our thinking about such matters. But yes, of course it matters hugely how one interprets the cognitive science relevant to metaethics.