James_Miller comments on Genes are overrated - Less Wrong

-11 Post author: taw 20 April 2011 12:03AM

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Comment author: James_Miller 20 April 2011 12:50:08AM *  8 points [-]

From 23andMe: (no non-members' link)

"Studies have shown that the odds of developing AD [Alzheimer's Disease] increases with each copy of the ε4 variant of APOE. One copy is associated with about two times increased odds of developing AD and two copies is associated with about 11 times increased odds in populations of European ancestry, compared to average."

20.3% of Europeans have just one ε4 variant and 1.7% have two of this variant.

23andMe rates the study as four stars meaning that " At least two studies examined more than 750 people with the trait or condition and/or the associations are widely accepted in the scientific community."

23andMe posted these results just a few days ago.