It's possible, but as DavidM says, one probably has to have rather unusual starting conditions.

My natural state of mind has, to the best of my admittedly spotty memory, always been essentially the same as what DavidM describes as stage four, and I've had at least one and possibly several experiences that match what he describes as enlightenment - I just never realized that they were particularly noteworthy or related to that until now. I'm good at meditating, in the sense of being able to just concentrate on one thing for a relatively long period of time (I find 10-15 minutes to be relatively effortless), but I've never made a habit of it.

I do find it plausible that meditation is the easiest way for someone whose native state is stage one to learn to enter and sustain stage four. I also find it plausible that drugs can accomplish that (I know of a particular, thankfully unusual, food additive that will send me into stage one, and avoid it like the bad trip that it is), but can't speak for specific ones.

ETA: Oh, except that I have no clue what he's talking about with 'vibrations', unless he's talking about a particular experience I've been known to have when improperly caffeinated. They aren't any usual part of my experience.