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Peter_de_Blanc comments on Seeing Red: Dissolving Mary's Room and Qualia - Less Wrong
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A physically plausible scenario would involve growing up under a monochromatic light source.
Growing up without sensory input actually affects the brain; see Wikipedia's article on monocular deprivation. I'm actually an example of this - I was born without the Mystic Eyes Of Depth Perception so I'll never know what stereoscopic vision "feels like".
I propose that "qualia" is a word that, like "microevolution", is mainly used by people who are very confused (and dissolving the question is the appropriate approach).
Depth perception can be gained through vision therapy, even if you've never had it before. This is something I'm looking into doing, since I also grew up without depth perception.
I should have been more precise. I was born without a fully formed right eye - it has no lens and does not transmit a signal to my brain. Therefore, no "therapy" can improve my Vision Onefold. People in my situation (monocular blindness from birth) are extremely rare, so your assumption is understandable.
I can get around in 3D space just fine, and I'm extremely good at first-person shooters, so I know I'm not missing much. (Coincidentally, I have no interest in physical sports.) The wiggle images do "work" for me.
(On the other hand, "Possession of a single Eye is said to make the bearer equivalent to royalty.")