I don't know... I think my preference for Colemak is something like that rather than eke out the last little bit of optimization out of my keyboard, I'd rather be able to tell people that I use Colemak than Quifimelewey. That I'll take the memetic social coherency of being able to signal something not too overwhelmingly weird and requiring of lots of explanation everytime you say it. I suppose you'd have to say "I used something designed in CarpalX".

Probably I will end up procrastinating about how to decide how to actually make this decision that will forever alter the course of the rest of my life rather than actually just picking one layout and immediately noticing improvements.