That's technically true, but in practice the results of selective breeding have undergone "staged deployment" - populations/farmers with harmful variants would have been selected against. Modern GMO can reach a global population much more quickly, so harmful variants have the potential to cause more widespread harm.
I was raised to believe that genetically-modified foods are unhealthy to eat and bad for the environment, and given a variety of reasons for this, some of which I now recognize as blatantly false (e.g., human genetic code is isomorphic to fundamental physical law), and a few of which still seem sort of plausible.
Because of this history, I need to anchor my credence heavily downward from my sense of plausibility.
The major reasons I see to believe that GMOs are safe are:
The major reason I see to believe that GMOs are dangerous is:
So: green goo, yes or no?