Sounds fun. I made a little video last month about what Hanson calls "Ems" that's supposed to grow into a bigger discussion on the political and social consequences. I call 'em "Uploads" though.

http://www.youtube.com/watch?v=RXAuglDs95s

That's more immediate-future rather than fifty years hence though. The script for later episodes talks more about their having failed to make any kind of AI work properly other than by scanning and uploading though, how learning facts is not the same as understanding with digs at the Cyc project.

If you're setting something further future I'd think a lot about exactly how this whole internet thing is going to be affecting social change over the next fifty years. Everyone's presumably connected wirelessly all the time, google and the wikipedia closer to everyone's brain than merely "at their fingertips". How does conversation change when everyone know everything there is to know about everything?