It's not so much that I have confidence that we can have unbounded improvements in any one of those fields, like genetic engineering for example; it's more that I would say there are at least 5 or 6 major research paths right now that could conceivably cure aging, all of which seem promising and all of which are areas where significant progress is being made right now, so that even if one or two of them prove impossible or impractical I think the odds of at least some of them eventually working are quite high.