Thanks! Upvoted since your responses are highly relevant to my questions.
I'm first looking at the arguments for the science of cryonics that Alcor gives. I do not have much expectation that I can judge all their claims to be valid or invalid yet, but I will give my general impression of the 3 main premises they present on their site here:
1.) Life can be stopped and restarted if cell structure and chemistry are preserved sufficiently well.
Arguments for this are point are based on currently verified procedures such as reviving people after their heart stops, people being revived long after drowning in cold water, freezing embryos, etc. I assume this is the reason you say "cryonics works" based on the history of medicine. I would change this to say that the likeliehood of cryonics working is greater in the universe we live in, because we can now revive people that would once have been irretrievably dead, so it is not inconceivable that people could be revived in the future from some states that would be considered irretrievably dead today. I have no disagreement with this point. I would note that the 'some' in the previous sentence is important since it means that it likely matters what strategy is used.
2) Vitrification (not freezing) can preserve biological structure very well.
This is an interesting argument and not one that I was previously aware of, nor of the fact that kidneys have been usable after vitrification or that a cat brain briefly regained EEG capability after vitrification. I thought the pictures were very helpful in showing the structural improvements Alcor says have been accomplished in this procedure, and this increases my confidence that this procedure could preserve information. I will need to look into this determine in more detail what we know about this process. Alcor is pretty clear that the toxicity of the procedure prevents brains from being revived this way today, so I definitely want to try to understand that aspect a little more. It is good to know that the process has improved in preserving visual structure over time, however.
3) Methods for repairing structure at the molecular level can now be foreseen.
True, although I'm not sure if this is an argument so much for cryonics in particular as for finding the most successful strategy for preserving information about that structure in some way. Cryonics may or may not be the best way to accomplish this, and if the best way is mutually exclusive to this method, I think that would be an important piece of information in making the most rational decision.
I will need to look at the other articles some more in the future. I skimmed over them but have not yet had the time to think them over and formulate a response. Thanks for responding to my questions about the available research in the field, the costs, and the opportunity cost.
On preservation methods: gwern has an article on plastination. It's compatible with cryonics in theory, but not currently in practice.
I distrust "this improves chances of revival with method X"-type reasoning, though. The argument for revival is more like "A huge advance among the many possible ones, only a few of which we can currently foresee" than "Scan and upload". This encourages catch-all preservation methods rather than methods that optimize for a particular kind of revival.
From Mike Darwn's Chronopause, an essay titled "Would You Like Another Plate of This?", discussing people's attitudes to life:
Conclusion, graphs, and references in article. As usual, I recommend reading Chronopause.com as Darwin has many good articles; to quickly link a few: