The natural response is to seek devastating arguments or just blurt out: "What makes you so special?"
A common reaction; I was reading up on the hostile wife phenomenon for a mini-essay on cryonics, and the quote from Robin Hanson's wife was quite striking (https://www.nytimes.com/2010/07/11/magazine/11cryonics-t.html):
“You have to understand,” says Peggy, who at 54 is given to exasperation about her husband’s more exotic ideas. “I am a hospice social worker. I work with people who are dying all the time. I see people dying All. The. Time. And what’s so good about me that I’m going to live forever?”
(As one commentator on, I think, Katja Grace's blog said - what's so bad about you that you should die?)
I found that article about Robin discouraging. He comes across to me as a geek version of Al Bundy, with 50 more IQ points, an academic job and a wife named Peggy who doesn't respect him. In fact, she holds her husband in so much contempt in the area of cryonics that it wouldn't surprise me if she has plans to cremate his body ASAP after his death to make sure he has no chance of "living forever."
Robin's marriage makes an interesting contrast with the marriage between Robert Ettinger and his second wife Mae. I got to meet Robert and Mae at cryoni...
From Mike Darwn's Chronopause, an essay titled "Would You Like Another Plate of This?", discussing people's attitudes to life:
Conclusion, graphs, and references in article. As usual, I recommend reading Chronopause.com as Darwin has many good articles; to quickly link a few: