Yes there's pretty good evidence that the physical structure of the brain is sufficient for long-term memories. The hard drive of your computer would survive if you unplugged your computer. Also if you put the RAM chips of your computer in LN2 immediately after powering off, the data would be readable later (or so I've heard). If human personalities were stored as dynamic processes, that would be a strong argument against cryonics, however this is unlikely to be the case; if they were, we would expect that hypothermia causes amnesia.
The damage done by the brain losing oxygen is mostly done later, after bloodflow has been restored. (This is known as the ischemic cascade.) It is not likely to be structurally damaging, provided there is prompt cooling. If there is adequate perfusion of cryoprotectants, the only damage is that of cryoprotectant toxicity, chilling injury, and cracking, none of which seem likely to render the structure unreadable or irreparable. All of these forms of damage are desirable to avoid (and each increases your risk), but none of them seem to me to be deal-killers.
I am guessing these problems can be resolved long before true antiaging therapies become possible, because it seems to be an inherently simpler problem. We already have a foot in the door so to speak, with the cryopreservation of tissue samples and even small organs such as the rabbit kidney. Note that unlike antiaging treatments, you can get immediate results, so even if they are comparable in difficulty, we should expect cryobiology to progress faster given the same amount of funding.
I find it hard to figure out whether the singularity is near or far. If it is near, that is an argument against not just cryonics but practically everything else. I tend to regard the singularity as moderately (but not ridiculously) low probability.
Yes there's pretty good evidence that the physical structure of the brain is sufficient for long-term memories. ... If human personalities were stored as dynamic processes, that would be a strong argument against cryonics, however this is unlikely to be the case; if they were, we would expect that hypothermia causes amnesia.
I was under the impression that hypothermia is not the same as cryonic freezing, and that even when a person is undergoing hypothermia, he still has brain activity. I am reasonably sure that the person is at least undergoing metaboli...
From Mike Darwn's Chronopause, an essay titled "Would You Like Another Plate of This?", discussing people's attitudes to life:
Conclusion, graphs, and references in article. As usual, I recommend reading Chronopause.com as Darwin has many good articles; to quickly link a few: