I can tell from "anterior cingulate cortext" that you are talking about a part of the brain, even though I haven't heard of that part before. (I may have been able to tell from context that much about "ACC", but it would have been more work, and I would have been less confident.)

And compare the Google searches for ACC and anterior cingulate cortext. It is nice to get a more relevant first search result than "Atlantic Coast Conference Official Athletic Site".