Genetic natural selection is done operating on people. There is no need to speculate about its future effects.
We will not be done with genetic natural selection till we give up the flesh, and perhaps not even then.
In populations recently exposed to the modern diet, and ill adapted to it, there has been significant genetic adaption in a couple of generations. S. G.; Ewbank, D.; Govindaraju, D. R.; Stearns, S. C. (2009). "Evolution in Health and Medicine Sackler Colloquium: Natural selection in a contemporary human population". Proceedings of the National Academy of Sciences 107: 1787. Similarly, populations recently exposed to alcohol.
There have been significant and substantial changes in skeletal structure over the last ten thousand years. One can reasonably define the white race in such a way that it is only ten thousand years old, that everyone before then was non white, not that we know what skin color they were. In Jamaica, we are arguably seeing sympatric race formation, as the upper classes develop a significant genetic difference from the lower classes.
Ashekenazi Jews have evolved very substantial genetic differences from Sephardic Jews since the crusades, even though they have single culture, and no one discriminates between them, they have become two quite different races, a single culture, a single folk, yet two races.
Ashkenazic and Sephardic Jews were first identified as distinct less than a millenium ago. That is fast. It took tens of thousands of years for Europeans to diverge from Africans. If Ashkenazim look different from Sephardim, it's because people living in northern Europe are more likely to marry northern Europeans, and people living in the Near East are more likely to marry Arabs.
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.
If continuing the discussion becomes impractical, that means you win at open threads; a celebratory top-level post on the topic is traditional.