From my perspective the big question is the magnitude of these effects: does this just reduce the marginal gain of more scientists/funding for science, or does it change the sign, so that beyond a certain point hiring more scientists actually slows progress? How costly are these false positive results?
Epidemiology is pretty expensive as it is. The sign seems to still be positive for spending more on scientists - diminishing returns have set in hard in some areas like pharmaceuticals, but I haven't heard of an actual net negative.
More evidence for this hypothesis:
Fanelli (2010). Do Pressures to Publish Increase Scientists' Bias? An Empirical Support from US States Data. PLoS ONE 5(4): e10271.