You can't conceive of for example some parts of the aging process just turning out to be much more complicated than we anticipated?
They already have. But at least they are now being researched whereas in the past they did not. We also already know of several potential viable antiagapic techniques, and simply need to determine their safety and delivery systems.
At this point, almost all the work we've done improving lifespan has been improving the average lifespan.
Yes. But up until two or so years ago no one in any mainstream capacity was doing any antiagapic research at all. That has changed. SENS is no longer a 'joke'. The caloric restriction gene activation project is also unlike any previous research done. There has been a change in the climate of medical science regarding the topic of senescence; it is no longer considered 'nutty' to find legitimate ways to reduce it.
So all statistics about how things have been up until now are irrelevant in making predictions about the future -- as the pieces in play have changed fundamentally.
(For some reasons to be a bit more pessimistic, see this earlier Less Wrong thread.
... Enter statistics about how things have been. :-)
But I'm puzzled by strong claims like not being able to conceive of a world-line.
From the here-and-now. I.e.; where there has already been successful antiagapic work, it is being taken seriously, and biomedical prosthetics are getting more sophisticated over time over and above the norm, and organ-level cloning has a viable route to practical application, etc., etc..
For these things to together not result in the above-described projection being valid would require that several different underlying principles of the world as I understand it be false. And while I can stipulate counterfactuals for purposes of discussion, I cannot legitimately conceive of things I believe to be inviolate truth being false.
For example; can you conceive of having never actually used a computer being the actual truth in the naive-reality sense? (Don't conjecturally imagine it; attempt to see if you could legitimately integrate that with your current status as having used such a machine.)
Yes. But up until two or so years ago no one in any mainstream capacity was doing any antiagapic research at all
Anti-aging research is always going on. How much interest mainstream science takes in it seems to be something close to a random walk.
For example, look at Alexis Carrel who won a Nobel Prize in 1912 and became more well known among both scientists and the general public not for his work that earned him that prize but for his apparently successful attempt to culture the cells of a chicken's heart for an indefinite amount of time. Many scient...
In a comment on his skeptical post about Ray Kurzweil, he writes,
I wonder how people on Less Wrong would respond to that poll?
Edit: (Tried to) fix formatting and typo in title.