Jordan comments on Rationality Drugs - Less Wrong
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I suffer from this as well. It is my totally unsubstantiated theory that this is a stress response. Throughout the whole day your body is tired and telling you to go to sleep, but the Conscious High Command keeps pressing the KEEP-GOING-NO-MATTER-WHAT button until your body decides it must be in a war zone and kicks in with cortisol or adrenaline or whatever.