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paper-machine comments on Rationality Quotes October 2011 - Less Wrong
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-- The Last Psychiatrist, "The Rise and Fall of Atypical Antipsychotics"
I went and read the original article and was massively entertained, mainly because I just studied for weeks to memorize all those drug names. I remember it saying in our textbook that the second-generation "atypical" antipsychotics had fewer side effects...and I was surprised because my friend is on a second-generation antipsychotic (Zyprexa) and at some point has had pretty much every possible side effect.
I read TLP with a giant grain of salt, because sometimes the things he says about the psychiatric profession just seem downright implausible.
Speaking as a person in the field - while true in general, in this particular case he is completely correct. Atypical antipsychotics have turned out to be massively misrepresented by the pharmaceutical companies. To avoid misunderstandings: I am a great supporter of pharmacological interventions, and I don't think that "Big Pharma" is an evil force, but this case has been one of the darkest spots on the image of the profession in the last decade.
The excellent and highly recommended "Mind Hacks" blog has been following the slow crash of the atypicals for a while. Latest can be seen here.
It reads like the writing of someone with an enormous axe to grind...