And the simple reason why it is so easy to fool psychiatrists with words like "atypical" and "tricyclic" is that most psychiatrists are stupendously ignorant of even kindergarten-level pharmacology and have barely any idea about how to interpret a study-- I don't mean p values, I mean looking at the y-axis; I mean the introduction. Much, much easier to base all of their arguments on empty terms that are nothing other than branding choices. Never mind the senseless term "atypical". Gun to head, is Seroquel an "antipsychotic" or an "antidepressant"? Confused? Sometimes a cigar is just a cigar, I guess.
-- The Last Psychiatrist, "The Rise and Fall of Atypical Antipsychotics"
I went and read the original article and was massively entertained, mainly because I just studied for weeks to memorize all those drug names. I remember it saying in our textbook that the second-generation "atypical" antipsychotics had fewer side effects...and I was surprised because my friend is on a second-generation antipsychotic (Zyprexa) and at some point has had pretty much every possible side effect.
Here's the new thread for posting quotes, with the usual rules: