This could be a dispute about the definition of SF: if you consider the core of SF to be something antithetical to "stylish postmodern cynicism," then maybe it has come on rough times. If you use the same definition the bookstores do, on the other hand, it's doing fine.
SIAI benefactor and VC Peter Thiel has an excellent article at National Review about the stagnating progress of science and technology, which he attributes to poorly-grounded political opposition, widespread scientific illiteracy, and overspecialized, insular scientific fields. He warns that this stagnation will undermine the growth that past policies have relied on.
Noteworthy excerpts (bold added by me):
In relation to concerns expressed here about evaluating scientific field soundness:
Grave indictors:
HT: MarginalRevolution