I cannot see how can anyone see 2001 as "inspiring hope".
Set in crapsack world of overpopulation, famine and imminent nuclear war, where human race was from the beginning a toy of omnipotent aliens. What hope? Our world in 2001 was not like in "2001", it was much better.
SIAI benefactor and VC Peter Thiel has an excellent article at National Review about the stagnating progress of science and technology, which he attributes to poorly-grounded political opposition, widespread scientific illiteracy, and overspecialized, insular scientific fields. He warns that this stagnation will undermine the growth that past policies have relied on.
Noteworthy excerpts (bold added by me):
In relation to concerns expressed here about evaluating scientific field soundness:
Grave indictors:
HT: MarginalRevolution