If you consider the contemporary struggle between Enlightenment values and Postmodern cynicism, Three Worlds Collide is definitely in the former camp. Its message is that no matter what happens, there is still a difference between right and wrong. I don't know what a postmodern answer to Three Worlds Collide would look like (someone should write one, please) but I imagine it would use moral error theory in place of moral realism.
SIAI benefactor and VC Peter Thiel has an excellent article at National Review about the stagnating progress of science and technology, which he attributes to poorly-grounded political opposition, widespread scientific illiteracy, and overspecialized, insular scientific fields. He warns that this stagnation will undermine the growth that past policies have relied on.
Noteworthy excerpts (bold added by me):
In relation to concerns expressed here about evaluating scientific field soundness:
Grave indictors:
HT: MarginalRevolution