Perfect prediction seems like a rather demanding criterion. I can't predict the behaviour of one of my cells perfectly - but that has more to do with difficulty in establishing initial conditions, a lack of knowledge of the laws of physics and computational intractability than it does with a lack of shared heritable material.

Also: some value drift within a single large organism may be seen as being permissible. The galactic federation may tolerate a few rebels - the point is more that it exhibits large scale unity and is not threatened by the rebels - because they are too few or too weak.

Serious disharmony would have to be something larger - disagreement about which side of the galaxy will launch an intergalactic colonisation mission, for instance.