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shokwave comments on Rationality Quotes November 2011 - Less Wrong
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The vast majority of untested chemicals-that-would-be-medicine are harmful or at least discomfiting. The vast majority of untested words-that-would-be-ideas are nonsense or at best banal.
(That is, part of knowing it's medicine vs knowing it's an idea is our prior for "this is harmful", and the relevant properties of ideas, medicine, human bodies, and human minds play a part here.)