JoshuaZ comments on 2011 Less Wrong Census / Survey - Less Wrong
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Increasing the number of possible weapons that can contribute to total war increases the chances that such a war will occur especially if the number of actors who have them goes up. Worse, if nanoweapons turn out to be easier to make than nukes once one has the basic knowledge, then a Saddam Hussein or a Ghaddafi type could easily ruin everyone's day.