All of it! Coma is not a state where temporal resolution is lost!
You can silence or deactivate neurons in thousands of ways, by altering one or more signaling pathways within the cells, or by blocking a certain channel. The signaling slows down, but it doesn't stop. Stop it, and you kill the cell within a few minutes; and even if you restart things, signaling no longer works the way it did before.
So even in something like the Milwaukee protocol there's still ongoing activity in every neuron? So what is different between human neurons and say those of C. elegans? They can survive substantial reductions in temperature with neuronal activity intact. Even bringing them down to liquid nitrogen temperatures leaves a large fraction surviving and that's true if they are cooled slowly or quickly. What am I missing here?
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