Annoyance was the feeling I got, as well. It seems to me that in the places he does not commit the fallacy of grey, he only restates limits that any LW-style transhumanist understands--ie, in an EM scenario without a friendly singleton, there will still be disease, injuries, and death; even given a friendly singleton, with meaningful "continuous improvement" we only get about 28,000 subjective years until the heat death of the universe, etc.