Robert Heinlein once claimed (tongue-in-cheek, I hope) that the "simplest explanation" is always: "The woman down the street is a witch; she did it." Eleven words - not many physics papers can beat that.
Faced with this challenge, there are two different roads you can take.
First, you can ask: "The woman down the street is a what?" Just because English has one word to indicate a concept, doesn't mean that the concept itself is simple. Suppose you were talking to aliens who didn't know about witches, women, or streets - how long would it take you to explain your theory to them?
All italicization is potentially also an allusion to something by EY.
Singularitarians frequently lament the irrevocably dead and the lack of widespread application of cryonics. Many cryonocists feel that as many lives as possible should be (and in a more rational world, would be) cryopreserved. Eliezer Yudkowsky, in an update to the touching note on the death of his younger brother Yehuda, forcefully expressed this sentiment:
Ignoring the debate concerning the merits of cryopreservation itself and the feasibility of mass cryonics, I would like to question the assumption that every life is worth preserving for posterity.
Consider those who have demonstrated through their actions that they are best kept excluded from society at large. John Wayne Gacy and Jeffrey Dahmer would be prime examples. Many people write these villains off as evil and give their condition not a second thought. But it is quite possible that they actually suffer from some sort of mental illness and are thus not fully responsible for their crimes. In fact, there is evidence that the brains of serial killers are measurably different from those of normal people. Far enough in the future, it might be possible to "cure" them. However, they will still possess toxic memories and thoughts that would greatly distress them now that they are normal. To truly repair them, they would likely need to have many or all of their memories erased. At that point, with an amnesic brain and a cloned body, are they even really the same person, and if not, what was the point of cryopreserving them?
Forming a robust theory of mind and realizing that not everyone thinks or sees the world the same way you do is actually quite difficult. Consider the immense complexity of the world we live in and the staggering scope of thoughts that can possibly be thought as a result. If cryopreservation means first and foremost mind preservation, maybe there are some minds that just shouldn't be preserved. Maybe the future would be a better, happier place without certain thoughts, feelings and memories--and without the minds that harbor them.
Personally, I think the assumption of "better safe than sorry" is a good-enough justification for mass cryonics (or for cryonics generally), but I think that assumption, like any, should at least be questioned.