All predictions are for 2012.

Homestuck:

Andrew Hussie releases at least one flash lasting longer than 10 minutes: 65%

Karkat, Terezi, John, Dave, Rose and Jade will not be permanently removed from story (Being killed off but returning as a ghost/sprite/whatever doesn't count as being permanently removed; being killed off and spending eternity in a dream-bubble and having no further contribution to the story does): 80%

The hints that Betty Crocker/Her Imperious Condesencion is running post-scratch Desrse will prove to be misdirection on Hussie's part: 20%

Baseball:

The San Francisco Giants will have a winning season. 80%

The Giants will make the postseason (either as NL West Champions or as a Wildcard team): 50%

Pablo Sandoval will hit at least 25 home runs: 80%

Ryan Braun will successfully appeal his suspension: 45%

Albert Pujols will finish the season with a batting average below .300: 65%