thomblake comments on Quantified Health Prize Deadline Extended - Less Wrong
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That explanation seems to require:
Already, there are a lot of substances I ingest that cause varying effects - increased productivity, increased creativity, increased fun, decreased pain - that each has its own tradeoffs. Even if it exists, I think the 'plateau' doesn't account for everything I care about, and there is obvious room for improvement.
And it would be really weird if the plateau didn't have some little peaks and valleys on it.