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irrationalist comments on Tell LessWrong about your charitable donations - Less Wrong
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Are there disadvantages to Oxfam? They looked pretty legitimate -- food, medicine, disaster relief, no history of fraud that I know of. Sort of the index fund of charities.
I'd still be surprised if their cost per human life saved is under $10,000. I suppose they aren't so bad in the scheme of megacharities, but your dollars have much greater marginal impact at a smaller, more focused charity. Or if you like the index fund strategy, then giving to GiveWell itself serves that purpose.