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orbenn comments on Rationality Quotes February 2012 - Less Wrong
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Is this true? Naive Googling yields this, which suggests (non-authoritatively) that blood sugar and moods are indeed linked (in diabetics, but it's presumably true in the general population). However, despair is not noted and the effects generally seem milder than that (true despair is a rather powerful emotion!)
Anecdotally: I'm not diabetic that I know of, but my mood is highly dependent on how well and how recently I've eaten. I get very irritable and can break down into tears easily if I'm more than four hours past due.