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ErnstMuller comments on The Unfinished Mystery of the Shangri-La Diet - Less Wrong
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What kind of rationalists are you? There is one way to lose weight with tons of research backing it, and perfectly valid molecular explanation how it works - one ECA pill every morning until you're done, if you're losing weight faster than 1kg/week definitely eat more as that's not very healthy.
You should behave like proper rationalists now, read some pubmed, order some pills, and lose as much weight as you want. No significant side effects observed, unlike "natural" dieting which causes hunger, loss of willpower, loss of energy etc. Your appetite will be so low you'll have to use alarm clock to remind yourself to eat, but it won't hurt when you do, so no willpower expended either way. Ask any random bodybuilder for advice if you need it, they mastered the art of getting rid of fat without harming rest of the body.
I'm 79 kg (bmi 22) down from 106 kg (bmi 30) five years ago, so unlike 95% of after-diet rebouncers I know what I'm talking about.
Messing with your feelings of hunger is seriously dangerous. Starvation leads to a massive biochemical response, among other things a excretion of endorphines, so you can get kicks from hunger. (That seems to be one of the ways anorexia works - http://www.ncbi.nlm.nih.gov/pubmed/22036318)
So, if you want to test the ECA- theory for yourself, be very, very careful. (I speak as a person with weak feelings of hunger which tends to forget to eat. I constantly battle against my tendency to lose weight, especially if stressed. That's no classical eating disorder - I'm very aware that I'm much to thin (BMI around 18). After approx. 2-3 days of low caloric intake (say, only breakfast and nothing else) hunger goes away completely and is replaced by feelings of euphoria and happiness. I suppose, this could happen to anyone who switches of his feelings of hunger. So, be careful, make and keep a timetable for meals!)
People with normal weight and higher (exact numbers depend on gender etc.) have a lot of adipose tissue, which absorbs and releases fuel all the time - after every meal there's excess energy, between meals and at nights there's deficit of energy, it actively manages that.
When you eat insufficient amount of food, your body tries to keep your energy in homeostasis by things like:
Your homeostasis will get what it wants somehow, and ECA tries to prevent it from doing it the way you don't want it to, so it's more or less limited to primarily relying on releasing fuel from adipose tissue. Trying to starve yourself, and willpower the hunger away works much worse than that.
If your adipose tissue cannot do that since it lacks sufficient stored fuel, your body will try the other things harder, and you may have some nasty side effects.
Anyway, who the hell would want to take ECA while being at BMI 18?
Maybe I've been a bit unclear. That may be because I'm no native writer of English.
The point I wanted to make was just "Be very, very careful if you start messing with your feelings of hunger." Self inflicted eating disorders are no fun.
(Also, there are a lot of people with eating disorders out there. Knowledge about starving more effective can be harmful to some people.)
And just to make it clear no one in their right state of mind would start taking ECA while being at BMI 18, the bit about my BMI was just anecdotal to make my point clearer. The nonanecdotal knowledge is in the link I provided, and a short search at Pubmed or Google Scholar should unearth more facts about hunger and it's psychic and physical effects.
I think you were very clear. As might be obvious from this thread, a lot of people have trouble believing in the range of human metabolisms.