Consider whether your journey is necessary - not travelling is always safer than travelling.

Consider what you can do to restructure your life to minimise the need for routine travel - Can you live closer to your place of employment/study, either by moving your home, or moving your employment/study? Can you work or study from home (at all? more often?)

I now live 20 minutes' walk from my employment instead of an hour's drive + 20 minute's walk, and there are many other benefits (much cheaper), but the safety improvements of not having to drive, especially as I have a sleep disorder that makes it impossible to always avoid driving when fatigued, are certainly one factor.

If you have to make a journey, consider alternatives to driving for all or part of the journey. All public transportation is much safer than driving; off-road public transportation (ie all rail except trams, flying) is safer still.

Remember that walking (strictly, crossing roads on foot) is higher risk than driving, so be prepared to go for a multi-modal journey to avoid walking in non-pedestrianised areas.