gwern comments on Harry Potter and the Methods of Rationality discussion thread, part 14, chapter 82 - Less Wrong
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There's an active prediction on PB.com that making Stones requires human sacrifice etc.
Only an issue if making the elixir consumes the stone (which is more what I was getting at) - one already exists, so it's a sunk cost.
It could also be an obstacle to mass production if the rate at which it can be produced with the existing supply of stones is insufficient to make enough volume for mass distribution.
The best "theory" I read was that only the person who makes the Stone can drink the Elixir, which would explain why only Mr and Mrs Flamel have benefited from it.