I imagine that a video of the uploaded worm moving in some artificial environment, reacting like a real worm, could be impressive. Even more impressive would be to test some genetic modifications on the virtual worm, which would also work on the real worm; e.g. an ability to eat some kind of waste we need to remove from environment. (I assume that with enough computer power, testing on virtual worms could be faster than testing real worms.)

Last but not least, when humans get uploaded, virtual worms could be used as a food source. :D