Lightwave comments on The True Epistemic Prisoner's Dilemma - Less Wrong
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In this scenario you can actually replace Omega with a person (e.g. a mad scientist or something), who just happens to be the only one who has, say, a cure for the disease which is about to kill a couple of billion people.
Then you may well be 99% sure of the truth of evolution, but can you be 99% sure of the judgement an admitted madman will make? If not, you should give more thought to cooperating.