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shminux comments on If calorie restriction works in humans, should we have observed it already? - Less Wrong
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Well, overeating is known to reduce the life expectancy in humans and other animals, and most animals tend to overeat when food is in abundance, so one logically hopes that reducing the calorific intake should give you a little extra time before you kick the bucket. Too bad it does not seem to work out this way.
This is referring to a significantly more specific claim than merely avoiding overeating - significantly restricting caloric intake below 'normal' levels.
(Upvoted to cancel a downvote on a post indicative of simply not knowing. Why would you downvote such a post without bothering to say something about it?)
My thinking was that if one assumes that there is a function: calories -> life expectancy, all else being equal, then the normal intake may or may not correspond to a local maximum. If it does not, then mild starving ought to increase life expectancy a bit. Of course, it tells us nothing about the global behavior, including significant restriction.
Oh, and I'm not sure what you meant about upvoting/downvoting. Not that it matters.