From the author profile:
Mattson traces his interest in aging back to his ninth-grade classroom. Asked then to write an essay on a scientific topic of his choice, he picked cryopreservation—the futuristic concept that humans can be resurrected after being suspended in the deep freeze for years. "I was grabbed with the idea of putting aging on hold," he now says.
The question is, does he post on Less Wrong?
Mail him and ask?
It appears that standard lab rats and mice are all morbidly obese. Using them as model organisms may give misleading results that fail to transfer to humans, or even to healthy rats and mice.
Article in the Slate.
PNAS version.
Does this reduce the whole calorie-restriction thing to nothing more than the advice to not be a fat slob? Well, maybe not, according to the author, but it has to make one wonder.